Spence, Van de Ven And Odobert To Start | 4-2-3-1 Tottenham Hotspur Predicted Lineup Vs Manchester United | OneFootball

Tottenham Hotspur will clash heads with Manchester United at Old Trafford this Saturday afternoon as they look to secure a good result on the road in the Premier League. Spurs managed to earn a hard-fought 2-2 draw versus Man City recently, which should keep them in good spirits going into this game.

Thomas Frank will set his side up in a 4-2-3-1 formation and is expected to make some changes to his starting XI for this clash. Djed Spence, Micky van de Ven and Wilson Odobert could all play from the start of this game.

4-2-3-1 Tottenham Hotspur Predicted Lineup To Face Manchester United

Defence

Guglielmo Vicario will feature in goal for Spurs after he shipped in a couple of goals in his last outing. Cristian Romero will function alongside Micky van de Ven at the heart of the Tottenham backline as they look to keep things solid at the back during the game.

Djed Spence will get the nod to impress as the right-back, while Destiny Udogie looks to prove his value on the other side as the left-back. Both of them will have to pick and choose their moments to join in on the attack.

Radu Dragusin will offer cover for the defensive positions on the bench.

LONDON, ENGLAND – FEBRUARY 01: Xavi Simons of Tottenham Hotspur in action during the Premier League match between Tottenham Hotspur and Manchester City at Tottenham Hotspur Stadium on February 01, 2026 in London, England. (Photo by Mike Hewitt/Getty Images)

Midfield

Conor Gallagher and Yves Bissouma will operate as the holding midfielders for Spurs. Their main job would be to make life tough for the home side in the middle of the park.

The talented trio of Randal Kolo Muani, Xavi Simons and Wilson Odobert will play just ahead of them as part of the Tottenham attack. All three of them will have to link up well if they want to cause some headaches for the Man United centre-backs on the counter.

Archie Gray and Pape Matar Sarr will be named on the bench and might come on to influence the game in the second half if required.

Attack

Dominic Solanke will lead the line for the North London club in the final third. He managed to score a brace against Man City recently, which should keep him in good spirits going into this game.

Mathys Tel will have to settle for a spot on the bench as he awaits his chance to make an impact in the latter stages of the game if needed.