Liverpool XI vs Atletico Madrid: Confirmed team news, predicted lineup and injury latest for Champions League | OneFootball

Alexander Isak could make eagerly-awaited debut in high-profile Anfield showdown

Liverpool open their Champions League campaign by welcoming Atletico Madrid to Anfield on Wednesday.

Arne Slot’s side take on Atleti for the first time since 2021, where they faced them twice in the old Champions League group stage format.

On both occasions, the English side emerged victorious, beating their Spanish counterparts 2-0 at Anfield and 3-2 at the Wanda Metropolitano. Both times Atleti had a man sent off, with Felipe dismissed in the first game, and Antoine Griezmann seeing red in the second.

Now, the big talking point is whether Alexander Isak will make his debut for his new club following his £125milllion move from Newcastle.

Liverpool’s other summer signings, including Florian Wirtz and Hugo Ekitike, could also be in line to make their European bows for their new employers, while Jeremie Frimpong is back in contention after he made his return from injury off the bench at the weekend.

Alexis Mac Allister could also play a part, while Curtis Jones’ situation remains unclear after he was missing from the squad against Burnley with a knock.

Isak and Mac Allister were both seen training with the squad on Tuesday, although Jones was nowhere to be seen.

Predicted Liverpool XI (4-2-3-1): Alisson; Frimpong, Konate, Van Dijk, Kerkez; Gravenberch, Mac Allister; Salah, Wirtz, Gakpo; Ekitike

Doubt: Jones

Time and date: 8pm BST on Wednesday September 17, 2025

How to watch: TNT Sports 1