Coppa Italia Round of 16: Lazio vs. AC Milan biggest fixture | OneFootball

The Coppa Italia Round of 16 fixture list is now complete, including Lazio vs. Milan, Roma vs. Torino, Juventus vs. Udinese and Inter vs. Venezia.

The tournament is structured around a tennis-style bracket, meaning the teams know who is coming up next after qualification.

The Second Round fixtures were rounded off this evening, with Torino and Genoa booking their spot in the next phase.

MILAN, ITALY – SEPTEMBER 23: Christopher Nkunku of AC Milan inflates a balloon as he celebrates with teammates after scoring to give the side a 2-0 lead during the Coppa Italia Frecciarossa Round of 16 match between AC Milan and US Lecce at Giuseppe Meazza Stadium on September 23, 2025 in Milan, Italy. (Photo by Jonathan Moscrop/Getty Images)

Without doubt, the biggest match scheduled for December is between Lazio and Milan, where the Biancocelesti will have the home advantage at the Stadio Olimpico.

These are again one-off games, to be decided after 90 minutes or on a penalty shoot-out, as extra time is not planned.

The only Serie B side still in the running is Venezia, who eliminated local rivals Verona on penalties to set up a clash with Inter.

COMO, ITALY – AUGUST 16: Anastasios Douvikas of Como 1907 celebrates after scoring their team’s second goal during the Coppa Italia match between Como 1907 and FC Sudtirol at Stadio G. Sinigaglia on August 16, 2025 in Como, Italy. (Photo by Marco Luzzani/Getty Images)

Coppa Italia Round of 16

Napoli vs. Cagliari

Bologna vs. Parma

Lazio vs. Milan

Juventus vs. Udinese

Atalanta vs. Genoa

Inter vs. Venezia

Roma vs. Torino

Fiorentina vs. Como