Southampton v Sheffield United: points to ease relegation pressure for both | OneFootball

Southampton host Sheffield United in the Championship on Wednesday, 21 January 2026 at St Mary's Stadium, with both sides looking to put distance between themselves and the relegation places in the second half of the season.

Southampton are unbeaten in the last six meetings with Sheffield United, winning five and drawing one across league and cup.

The Saints are without a league win in five, though they did win at Doncaster in the FA Cup. The Blades have two league victories from their last four but lost at Charlton last time out and were edged out 4-3 by Mansfield in the cup.

The Saints are set to be without Mads Roerslev, Cameron Bragg and Shea Charles through injury. The Blades miss Japhet Tanganga and Djibril Soumaré due to suspension, while Tyler Bindon is injured.

Saints tend to control games, averaging 58% possession with 84.67% passing accuracy, and could again look to feed Adam Armstrong, the league's top scorer with 11 goals, while Finn Azaz has seven. The Blades' resilience shows in seven clean sheets and a league-high 601 aerial duels won, and Callum O'Hare's seven goals and five assists offer their main supply line. Wide delivery may be a route for both given their crossing volumes.

The Saints sit 16th on 33 points and would move to 36 with a win, which could pull them further from danger. The Blades are 18th with 32 and would reach 35 with victory, potentially easing the pressure above the relegation zone.