Liverpool vs Southampton – Predicted lineup and team news

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The Football Faithful

·23 September 2025

Liverpool vs Southampton – Predicted lineup and team news

Liverpool begin their Carabao Cup campaign on Tuesday night, aiming to continue a blistering run of form that has seen them win their last six consecutive matches.

The Reds host Championship side Southampton at their Anfield fortress, where they are unbeaten in nine competitive games and have a phenomenal recent record against their opponents.

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After reaching the final of this competition last season, Arne Slot will be keen for another deep cup run. While the manager will use this fixture to rest key players and give minutes to his wider squad, the expectation remains a professional performance. A convincing win would maintain the team’s high confidence levels ahead of a busy fixture schedule.

Liverpool vs Southampton – Predicted lineup and team news

Liverpool team news

Arne Slot has confirmed he will make wholesale changes to his side for the visit of Southampton. Key players Mohamed Salah, Virgil van Dijk, Ibrahima Konate, Dominik Szoboszlai, and Ryan Gravenberch will all be given the night off. As a result, Giorgi Mamardashvili is set to start in goal behind the likely centre-back pairing of Joe Gomez and Giovanni Leoni.

In midfield, veteran Wataru Endo will probably be partnered by teenager Trey Nyoni. The attack will also see a complete refresh. Federico Chiesa, Curtis Jones, and Rio Ngumoha are expected to support striker Alexander Isak.