Van de Ven And Simons To Start | 4-2-3-1 Tottenham Hotspur Predicted Lineup Vs Atletico Madrid | OneFootball

Tottenham Hotspur will welcome Atletico Madrid at the Tottenham Hotspur Stadium this Wednesday night as they look to earn a good result in the second leg of their UEFA Champions League last-16 tie. Spurs managed to grind out a 1-1 draw away at Liverpool recently, which should give them some confidence going into this game.

Igor Tudor will opt for the 4-2-3-1 formation and is expected to make some changes to his first team for this game. Micky van de Ven, Randal Kolo Muani and Xavi Simons could all get the nod to impress from the start of this game.

4-2-3-1 Tottenham Hotspur Predicted Lineup To Face Atletico Madrid

Defence

Guglielmo Vicario will feature in between the sticks for the North London club after he conceded one goal in his last appearance. Kevin Danso will operate alongside Micky van de Ven at the heart of the Tottenham backline as they look to maintain a solid shape on the defensive end of the field.

Pedro Porro will try to put in a good performance as the right-back, while Djed Spence hopes to give a good account of himself on the other side as the left-back. Both of them will have to pick and choose their moments to join in on the attack.

Radu Dragusin will provide cover for the centre-back positions on the bench.

LIVERPOOL, ENGLAND – MARCH 15: Kevin Danso of Tottenham during the Premier League match between Liverpool and Tottenham Hotspur at Anfield on March 15, 2026 in Liverpool, England. (Photo by Michael Regan/Getty Images)

Midfield

Archie Gray and Pape Matar Sarr will operate as the defensive midfielders as they try to make life tough for the visitors at the centre of the park.

The talented trio of Mathys Tel, Xavi Simons and Randal Kolo Muani will function just ahead of them as part of Tudor’s attack. All three of them need to combine well if Spurs want to orchestrate enough chances to win this clash.

Souza and Callum Olusesi will make up the numbers on the bench as they await their chance to make an impact in the second 45 minutes if needed.

Attack

Dominic Solanke will lead the line for the London giants up top. He has to find a way to be a real threat in the final third.

Richarlison will be named on the bench and might come on to influence the game in the final quarter if Tottenham are in need of a goal by then.