Serie A official line-ups: AC Milan vs. Roma | OneFootball

Milan form a new partnership of Rafael Leao and Christopher Nkunku amid an injury crisis, while Roma can go clear at the top of the table with Paulo Dybala and Matias Soulé.

It kicks off at San Siro at 19.45 GMT.

You can follow all the build-up and action as it happens from today’s five Serie A games on the Liveblog.

ROME, ITALY – MAY 18: Gianluca Mancini of AS Roma scores his team’s first goal past Mike Maignan of AC Milan during the Serie A match between AS Roma and AC Milan at Stadio Olimpico on May 18, 2025 in Rome, Italy. (Photo by Paolo Bruno/Getty Images)

This is a huge head-to-head at the top of the table, as after Napoli were held to a 0-0 draw by Como, a win here would send Roma clear as the new sole leaders.

However, a Milan victory would put Max Allegri’s side level with Roma, and one point off first place.

The Rossoneri have an injury crisis to deal with, missing Santiago Gimenez, Christian Pulisic and Adrien Rabiot, while Pervis Estupinan and Ardon Jashari are only fit for the bench.

Fikayo Tomori is also dealing with a knee issue, but there is an all-new strike partnership of Rafael Leao and Nkunku in the 3-5-2 formation, supported by Luka Modric and Samuele Ricci.

ROME, ITALY – OCTOBER 29: Paulo Dybala of AS Roma in action during the warm up before the Serie A match between AS Roma and Parma Calcio 1913 at Stadio Olimpico on October 29, 2025 in Rome, Italy. (Photo by Paolo Bruno/Getty Images)

Roma have some concerns too, as Angelino is still out after suffering from pneumonia, while Evan Ferguson is going to need at least a couple of weeks following an ankle sprain.

The big doubt for Gian Piero Gasperini remains whether to pick a genuine centre-forward or use Dybala as a False 9.

Artem Dovbyk had been linked with Milan as part of a potential swap with Gimenez, but the Ukrainian is on the bench here, as Dybala and Soulé form the all-Argentine front two.

Mario Hermoso is again in the back three, with Zeki Celik and Wesley on the flanks.

There will be an emotional minute’s silence before kick-off for Giovanni Galeone, who died today at the age of 84, as he was a mentor to both Allegri and Gasperini.

ROME, ITALY – OCTOBER 29: Matias Soule of AS Roma kicks the ball during the Serie A match between AS Roma and Parma Calcio 1913 at Stadio Olimpico on October 29, 2025 in Rome, Italy. (Photo by Paolo Bruno/Getty Images)

Milan vs. Roma line-ups

Milan: Maignan; De Winter, Gabbia, Pavlovic; Saelemaekers, Fofana, Modric, Ricci, Bartesaghi; Leao, Nkunku

Roma: Svilar; Hermoso, Mancini, N’Dicka; Celik, Cristante, Koné, El Aynaoui, Wesley; Soulé, Dybala

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