Champions League & Europa League Picks: Serie A Teams Midweek Forecasts | OneFootball

Europe’s elite club competitions return to action this midweek, with several Serie A sides seeking redemption for disappointing starts. Except for Inter, who enjoyed a perfect opening to their Champions League campaign, all other Italian teams have struggled in continental action.

Juventus manager Igor Tudor is on the precipice of an early dismissal, and the upcoming trip to the Santiago Bernabeu to take on Real Madrid doesn’t bode well. However, Atalanta can realistically hope to post their second consecutive league phase victory at Europe’s top table against Slavia Prague.

In the lower echelons, Scudetto hopefuls Roma will look to bounce back from Saturday’s domestic failure when they lock horns with Viktoria Plzen at the Stadio Olimpico. With major European fixtures on the horizon, there’s a growing enthusiasm among bettors.

As anticipation builds across Europe, the excitement mirrors the surge in Missouri sports betting, where fans are keen to back their favorites in the latest continental showdowns. Without further ado, let’s look at our best picks for the upcoming UEFA clashes featuring Italian clubs.

Atalanta vs Slavia Prague

Following a sobering 4-0 defeat at reigning holders Paris Saint-Germain on matchday one, Atalanta pulled off a stunning comeback to beat Club Brugge 2-1 at home last time out. However, Ivan Juric’s men have since drawn back-to-back league matches, netting just one goal in the process.

Worryingly, La Dea have only won three of their last 14 home outings in the Champions League main draw (D5, L6). Therefore, a second consecutive home victory at Europe’s top table for only the second time in the club’s history is not a foregone conclusion.

Yet, Slavia Prague’s visit could be just what the doctor ordered for the Bergamo outfit. Indeed, the Czech champions have already lost in Italy this season, slumping to a 3-0 defeat against Inter in the previous round. That result deepened Slavia’s woes on Italian soil, where they’ve lost nine of their last ten matches (D1).

Real Madrid vs Juventus

Xabi Alonso’s regime is taking shape as Real Madrid head into proceedings on the back of three consecutive wins in all competitions, capped by a narrow 1-0 La Liga triumph over Getafe last weekend. Interestingly, that inspiring run started with a 5-0 rout of Champions League debutants Kairat Almaty in the previous round.

Los Blancos boast a perfect record after the opening two matchdays (W2) and will look to make it three wins from three against an out-of-sorts Juventus. After five successive draws in all competitions, including two in the Champions League, the Bianconeri slipped to a 2-0 league loss at Como on Sunday.

As a result, Tudor has come under heavy scrutiny, with Juventus already searching for replacements. Still, revenge could be a powerful motivator, with the Turin club aiming to settle the score with the record-time European champions following a heartbreaking 1-0 defeat in the 2025 FIFA Club World Cup quarter-finals.

Despite Jonathan David’s torrid start to life in Serie A and Dusan Vlahovic’s inconsistent form, Juventus still possess enough firepower to get on the scoresheet. However, Real Madrid should ultimately take all three points.

Roma vs Viktoria Plzen

A dismal 1-0 home loss to Inter on Saturday evening dampened Roma’s spirits ahead of this showdown, marking their second defeat in three matches. Gian Piero Gasperini’s side will be out to make amends and erase the memory of another 1-0 home loss to Lille in the last Europa League round.

Stadio Olimpico is no longer the impregnable fortress it once was, with the Giallorossi losing three of their last four fixtures on home turf (W1). Optimism comes from Roma’s recent H2H record against Plzen as they’ve only lost one of the four previous meetings between the sides (W2, D1).

Against this backdrop, Roma have claimed just five wins across their 12 UEFA clashes against Czech opposition (D3, L4). On the bright side, visiting Plzen have suffered five defeats in seven away matches against Italian clubs in major European competitions (W1, D1).

With that in mind, Roma’s win looks like a virtual certainty. Additionally, it’s not unreasonable to expect Gasperini’s side to spice things up with a prolific performance for a change.