Serie A official line-ups: Inter vs. Pisa | OneFootball

Francesco Pio Esposito and Lautaro Martinez lead the Inter attack in a home Serie A match against Pisa.

It kicks off at 20:45 CET (19:45 GMT), and it’s the opening match of Serie A Week 22

You can follow all the build-up and action as it happens from this game on the Liveblog.

Denzel Dumfries and Hakan Calhanoglu are still unavailable for the home side, and Cristian Chivu slightly rotates his team ahead of next week’s Champions League encounter with Borussia Dortmund.

PISA, ITALY – NOVEMBER 30: Michel Aebischer of Pisa Sporting Club in action against Francesco Acerbi of FC Internazionale during the Serie A match between Pisa SC and FC Internazionale at Arena Garibaldi on November 30, 2025 in Pisa, Italy. (Photo by Gabriele Maltinti/Getty Images)

Marcus Thuram rests, making room for Pio Esposito up front, while Lautaro Martinez gets the nod again.

Carlos Augusto starts as a left midfielder in place of Federico Dimarco, Nicolò Barella starts on the bench with Henrikh Mkhitaryan, Petar Sucic and Piotr Zielinski in central midfield.

Pisa have several players out of action, including Raul Albiol, ex-Inter winger Juan Cuadrado, Mateus Lusuardi, and Adrian Semper.

PISA, ITALY – DECEMBER 27: Manager of Pisa Sporting Club Alberto Gilardino reacts during the Serie A match between Pisa SC and Juventus FC at Arena Garibaldi on December 27, 2025 in Pisa, Italy. (Photo by Gabriele Maltinti/Getty Images)

January signing Rafiu Durosinmi, who scored on his debut against Atalanta last week, begins on the bench as Henrik Meister, Matteo Tramoni and Stefano Moreo are picked up front in Pisa’s 3-4-2-1 system.

Official line-ups: Inter vs. Pisa

Inter (3-5-2): Sommer; Bisseck, De Vrij, Bastoni; Luis Henrique, Sucic, Zielinski, Mkhitaryan, Carlos Augusto; Lautaro, Esposito. ​ ​Pisa (3-4-2-1): Scuffet; Coppola, Calabresi, Canestrelli; Touré, Marin, Aebischer, Angori; Tramoni, Moreo; Meister.